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Systems Club I – Calcium Imaging Pipeline:

Biozentrum 1 Hanns-Dieter-Hüsch-Weg 15, Mainz, RLP, Germany

From Data Acquisition to Analysis The field of optical calcium imaging, particularly of individual neuron function in the intact tissue, relies on detecting subtle changes in light intensity. The implementation of 2-photon microscopy in combination with calcium indicators allowed for the first time a functional readout of neuronal circuits comprising of several hundred neurons in… Read More »Systems Club I – Calcium Imaging Pipeline:

Systems Club II – Mouse Behavioral Tracking

Biozentrum 1 Hanns-Dieter-Hüsch-Weg 15, Mainz, RLP, Germany

Methods for deriving Resilience against stress in mice from long term observations When individuals in major psychological or physical stressful situations are able to maintain their mental health or restore it quickly after a short period of experiencing stress-related symptoms, this is referred to as resilience. The classification of mice into resilient and susceptible animals… Read More »Systems Club II – Mouse Behavioral Tracking

Systems Club III – Light Sheet Microscopy

Biozentrum 1 Hanns-Dieter-Hüsch-Weg 15, Mainz, RLP, Germany

Deeper Insights: Exploring LSM in Combination with Tissue Clearing Light Sheet Microscopy (LSM) allows revolutionizing high-speed, high-resolution imaging and reduced photo-toxicity, proving invaluable in whole-organ and whole-organism imaging. The combined power of LSM with tissue clearing now offers unparalleled views of intact organ structures, fostering comprehensive investigations and rich insights into the cellular landscape.The Systems… Read More »Systems Club III – Light Sheet Microscopy